Neuroma under the skin - A neuroma is a localized swelling and irritation of a nerve. Blunt trauma (a blow) to the front of the knee can bruise the fine sensory nerves that lie just under the skin and can lead to neuroma-like pain.
Gentle scratching of the skin with a thumbnail or squeezing of the skin is painful. The diagnosis is confirmed by relief being obtained with an injection of an anesthetic under the skin.
This is a common condition among people who bang their knee on a hard object such as the dashboard of a car or simply the ground.
Note that neuroma-like conditions will not appear on any imaging study.
Osteochondritis dissecans (OCD) - This is a somewhat mysterious condition occurring in teenagers and young adults. It affects the bone that lies at the very end of a bone (such as the femur), directly under the articular cartilage ('gristle').
The area of bone that is affected is usually small. It becomes more or less separated from the rest of the bone and is painful. It rarely occurs in the knee cap, but when it does it is not likely to heal on its own.
Surgery is likely to be recommended to keep it in position and prevent it from breaking off into the joint.
Tumors - The patella is not a common site for tumors, but a number of benign and malignant neoplasms (cancers) have been reported.
Infection - Osteomyelitis (infection of the bone) in adults is relatively uncommon, and this is particularly true of the patella.
If other signs and symptoms of infection are present, however, or if the host is particularly immuno-compromised (unable to fight infection), the diagnosis should be considered. A patellectomy (removal of knee cap) is an option in severe or intractable cases.
Osteochondritis dissecans is not common, but it is very important to exclude it. Failure to do so in an early stage may make the difference between a cure and a disaster.
The same applies to infection and tumors.
Careful examination of the x-ray is mandatory. In particular, one needs to be aware of discrete signs which may indicate osteochondritis dissecans, tumor or infection.