2009 - Prophylaxis of Heterotopic Ossification of the Hip

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Dr Sheila Strover

Clinical Editor

Dr Sheila Strover is the Founder and previous Clinical Editor of the KNEEguru website.Her medical studies were completed at the University of the Witwatersrand in South Africa - BSc(Hons) (1968) and MBBCh (1974). She emigrated to the United Kingdom in 1983 and worked as an anaesthetist (anaesthesio…

January 1, 2009

An 'interpretation' of a 2009 medical paper talking about bony change of the soft tissue around a joint implant, and comparing the use of anti-inflammatories and radiation in preventing these changes.

Prophylaxis of Heterotopic Ossification of the Hip. Systematic Review and Meta-Analysis.

Vavken P, Castellani L and Sculco TP. Clin Orthop Relat Res (2009) 467:3283–3289.

This is the editor's interpretation of a paper published in the orthopaedic literature in 2009 - our attempt to make relevant medical articles accessible to lay readers. If you wish to read the original it is easy to ask your librarian to obtain a reprint for you from any medical library.

Although this paper relates to the hip, the conclusions almost certainly are relevant to heterotopic ossification of the knee as well when the authors of this paper after extensive literature search state "we found no evidence for a statistically significant or clinically important difference between NSAIDs or radiation in preventing HO."