Osteochondral defect

Written by Dr Sheila Strover on March 14, 2025

An osteochondral defect occurs when a chunk of joint cartilage is lost, leaving a crater that extends into the underlying bone. Page updated July 2024 by Dr Sheila Strover (Clinical Editor)

osteochondral defectosteochondritis dissecans of femoral condyle

What causes an osteochondral defect?

Deep craters involving both the cartilage and the bone may be a result of impact or a condition such as osteochondritis dissecans where blood supply fails to an area of bone, and the bone and cartilage die.

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What happens to an OCD without surgical intervention?

The defect is likely to cause pain and altered mobility, but the real issue is that without closing the defect it is likely to extend and lead eventually to arthritis.

Peer-reviewed papers
  • Quote from peer-reviewed paper:

    "....Osteochondral defects of the knee significantly alter the biomechanics of the joint. This can cause symptomatic and functional impairment as well as considerable risk of progressive joint degeneration...."

    Citation: Howell M, Liao Q, Gee CW. Surgical Management of Osteochondral Defects of the Knee: An Educational Review. Curr Rev Musculoskelet Med. 2021 Feb;14(1):60-66. doi: 10.1007/s12178-020-09685-1. Epub 2021 Feb 15. PMID: 33587261; PMCID: PMC7930143.

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Options for cartilage repair of an osteochondral defect

There are a number of possible cartilage repair procedures for attempting to fill the defect back to a congruent cartilage surface.

The big number suggests that none are in fact perfect! Possible interventions include:

Peer-reviewed papers
  • Quote from peer-reviewed paper:

    "....the re-operation, re-intervention and adverse event rates were similar for all procedures. However, microfracture demonstrated the worst patient-reported outcomes, with particular emphasis placed on the poor long-term results of this operation...."

    Citation: Howell M, Liao Q, Gee CW. Surgical Management of Osteochondral Defects of the Knee: An Educational Review. Curr Rev Musculoskelet Med. 2021 Feb;14(1):60-66. doi: 10.1007/s12178-020-09685-1. Epub 2021 Feb 15. PMID: 33587261; PMCID: PMC7930143.

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